The agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is standard for the induction of Parkinson’s disease (PD) in animal models. Cognitive dysfunction disturbs about thirty-forty percent of PD patients and can progress to dementia. Non-motor symptoms, such as hippocampal dama...
Self-reported anthropometric data are widely used in public health for convenience and cost-effectiveness, yet gender-specific reporting biases raise accuracy concerns among young adults in Abakaliki, Nigeria. A descriptive cross-sectional design was employed, recruiting 240 participants (1...
Little is known about the ketogenic diet (KD)'s seizure-fighting properties. The substantia nigra pars reticulata (SNr) is a "gate" site for seizures. The neuroprotective effect of KDs on PTZ-induced epilepsy (35 mg/kg) every other day for 20 days was examined. The thirty mature female Wist...
There are increasingly significant safety concerns regarding the use of medicinal plants with regard to maternal and fetal health. This is particularly due to the established capacity of some bioactive compounds like phytoestrogens, saponins, and others to influence reproductive hormone lev...
Anatomy is a core component of health sciences education, yet it remains challenging, particularly in resourceconstrained settings. This study examined the relationship between students’ perceptions, expectations, and learning challenges among undergraduate anatomy students at Al-Hikmah ...
Body mass index is widely used in adolescent nutritional assessment, but it cannot differentiate between fat mass and lean body mass, and its utility may be strengthened by simple circumference-based measurements. This study assessed the relationship between wrist circumference and BMI-rela...
Executive function (EF) comprises cognitive processes essential for academic success. This study assessed the relationship between executive function and self-assessed academic performance (AP) among medical students at Enugu State University of Science and Technology (ESUT). A cross-sectio...
The scapula is a key anatomical structure reflecting locomotor adaptation in primates. Humans exhibit bipedalism with non-weight-bearing upper limbs, whereas arboreal primates such as Cercopithecus sclateri rely on forelimbassisted locomotion. Forty adult dry scapulae (20 humans, 20 Sclater&rs...
Porters in large Nigerian markets are routinely exposed to repetitive lifting and load carriage. This study aims to build and deploy a machine learning model to predict the risk of back pain from anthropometric parameters. A descriptive cross-sectional study was conducted among 300 active p...
Climate change-induced heat waves pose significant physiological challenges to organisms, yet the sublethal effects of acute heat stress on living organism’s health remain poorly understood. This study investigated the effects of acute heat stress (5 and 10 minutes at an elevated temp...
Schizophrenia is a complex neurodevelopmental disorder influenced by genetic and prenatal environmental factors. Dermatoglyphic traits, particularly fingerprint ridge density (RD), are established during early foetal development and may serve as non-invasive markers of developmental disturb...
Testicular cell toxicity can be a resultant effect of exposure to environmental pollutants such as lead (Pb) through mechanisms including oxidative stress, inflammation, and endocrine disruption, thereby impairing male reproductive function. This study evaluated the protective effect of zin...
Cannabis use during pregnancy is increasing globally, raising concerns about fetal exposure to Δ9- tetrahydrocannabinol (THC), the principal psychoactive constituent of cannabis. THC readily crosses the placental barrier and may disrupt the endocannabinoid system, which regulates feta...
Cyclophosphamide (CP) is an alkylating chemotherapy agent that causes severe, dose-limiting ovotoxicity, often leading to diminished ovarian reserve. This study investigated the protective efficacy of magnesium glycinate (MgG), a highly bioavailable organic magnesium chelate with antioxidan...
Diabetes mellitus is estimated to affect over 589 million globally, with projections reaching 853 million by 2050, and a higher burden reported in sub-Saharan Africa. The disease is characterized by destruction of pancreatic βcells and persistent hyperglycemia. Limitations associated with...
Diabetes mellitus and mercury toxicity are associated with oxidative stress and neuronal degeneration, particularly in the hippocampus. The study assessed histological and immunohistochemical effects of ethanol leaf extract of Chromolaena odorata on the hippocampus of alloxan-induced diabet...
Sociodemographic characteristics such as age, education, income, marital status, and occupation significantly influence lifestyle behaviors among women. These factors vary across settlement types (urban, suburban, and rural), shaping health outcomes and accessibility to healthcare. This stu...
The hypothalamic–pituitary–gonadal (HPG) axis is central to male reproductive function, and its disruption contributes to infertility. Asparagus officinalis leaves, less studied than roots or shoots, contain bioactive compounds with antioxidant and androgenic properties. This st...