Nigerian anatomy education offers valuable intellectual breadth, yet many students and graduates struggle to connect their qualifications in anatomy with clearly recognized professional roles. This editorial argues that the problem is institutional rather than individual. Specialization may impro...
Aluminium chloride (AlCl?) is a widely used industrial reagent with well-documented nephrotoxic properties, capable of inducing significant oxidative stress, inflammation, and structural renal damage. This study evaluated the nephroprotective potential of the ethanolic leaf extract of Eupho...
Monosodium glutamate (MSG) is widely used as a flavor enhancer and has been associated with oxidative and reproductive disturbances in experimental models. This study investigated the protective effects of Momordica charantia against MSG-induced ovarian toxicity in adult female ...
Sex-related biological differences influence how the nervous system responds to toxic exposures. These differences may determine the severity and pattern of neuronal injury produced by environmental neurotoxicants such as insecticides. λ-Cyhalothrin (LCT), a widely used type II pyret...
Hyperglycemia is associated with hippocampal neuronal injury, apoptosis, and demyelination; Modulation of apoptotic pathways, particularly Bcl-2 associated X protein (BAX) and B-cell lymphoma 2 (Bcl-2) signaling, represents a potential therapeutic target for neuroprotection. Thi...
This study investigated the laxative effects of aqueous Senna siamea leaf extract (Yellow Cassia), an Asian medicinal plant widely used in Nigerian ethno-medicine, on loperamide-induced constipation in thirty female Wistar rats. The rats were separated into five groups (n=6) to ...
Depression is a major neuropsychiatric disorder, and limitations of current antidepressants have stimulated interest in plant-derived therapies. Hyphaene thebaica (doum palm) contains bioactive compounds with reported neuroprotective and antioxidant properties. This study evalua...
Acute inflammation is associated with edema and membrane destabilization. Medicinal plants and antioxidant compounds are increasingly explored as safer anti-inflammatory agents. Bambara groundnut, Vigna subterranea, is commonly used in folkloric medicine. Scientific validations ...
Schizophrenia and related psychiatric disorders are often characterized by hippocampal dysfunction and demyelination. Cuprizone (CPZ), a copper chelator, is commonly used to induce neurotoxicity and oxidative stress in rodent models to mimic these dysfunctions. This study invest...
Depression and anxiety are common stress-related neuropsychiatric disorders associated with impaired neuroplasticity, oxidative stress, neuroinflammation, and altered cellular energy metabolism. Nicotinamide, a precursor of nicotinamide adenine dinucleotide (NAD?), has emerged a...
Cephalopelvic disproportion (CPD) is a major cause of obstructed labor and operative delivery worldwide, contributing to maternal and neonatal morbidity and mortality in low- and middle-income countries. Traditional antenatal prediction of CPD relies on linear fetal anthropometr...
Postmortem interval (PMI) estimation is central to forensic death investigation, yet taphonomic data from tropical West Africa remain scarce. Furthermore, only a few published Nigerian studies have examined how clothing interacts with body mass in hanged decomposing carrion. Fou...
Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder characterized by hyperandrogenism, metabolic disturbances, and ovarian dysfunction. This study investigated the effects of ethanolic leaf extract of Phyllanthus amarus on ovarian histomorphology and se...
Oxidative stress and neuroinflammation play a central role in the pathogenesis of numerous neurological disorders by disrupting cellular redox balance and promoting neuronal degeneration. Phenylhydrazine (PHZ), a well established inducer of oxidative stress and hemolytic anemia, gener...