Environmental and occupational exposure to heavy metal-containing products, such as crude oil, poses serious global health concerns. The bioaccumulation of crude oil constituents in humans has been reported to be toxic to the brain, however, much is still unknown about the neurotoxic mechanism of cr...
Squirrels have attracted many interests from many scientists as a model for research. There are several species of squirrels found across the globe; however, different species are found in specific locations. This study examined the Thomas'-Rope-Squirrel (TRS) and Gambian-Sun-Squirrel (GSS), mostly ...
The first step in evaluating toxicity of a substance is to test for acute toxicity of that substance. The focus of acute oral toxicity is on possible short-term adverse effects from one or more oral exposures given within a 24-hour period. The purpose of this research was to investigate the effects...
In this study, the cardio-renal health of offspring of mother exposed to bonny light crude oil (BLCO) during gestation was assessed in Wistar rats. Ten pregnant rats were divided into 2 groups (n=5). Distilled water (0.75 mL/Kg/days) was administered to group 1 while BLCO (0.75 mL BLCO/Kg/day) was a...
The most prevalent malignant tumor in humans is basal cell carcinoma (BCC), and its frequency has been rising over time. This study examined the histological subtypes of cutaneous BCC identified at the Federal Medical Centre, Umuahia, Nigeria. The study examined the histological subtypes of cutaneou...
Diabetes mellitus contributes to male sexual dysfunction and infertility by causing oxidative damage to the testis. Over the years, the use of herbs like Hibiscus sabdariffa for the treatment of ailments has garnered worldwide recognition. However, its impact on male infertility due to Type1 diabete...
Doxorubicin (DOX) is a chemotherapeutic agent that exhibits splenotoxicity and induce hematopoietic suppression in cancer patients. Gallic acid is an antioxidant and anti-tumor agent that protects non-cancer cells. Sixteen rats were randomly grouped into four (4) sub-groups of 4 rats. The control re...
Permethrin is a commonly used domestic insecticide with varying degrees of neurotoxicity in both insects and mammals. The phytochemical components of Moringa oleifera oil (MOR) have several health benefits including antioxidative and anti-inflammatory properties. This study investigated the role of ...
Groundnut (Arachis hypogaea) is an annual legume crop grown mainly for its edible seeds. It is very nutritive and considered to be healthy for human diet because of its health benefits. However, individuals have been observed to react to its different processed forms. This study, as a two phase stu...
A cure to type 1 diabetes without undesirable side effects still remains a formidable challenge in drug research and development. Many traditional plants and herbal medicines have been discovered to have favourable and safe anti-diabetic activity in comparison to synthetic drugs. This study was aime...
Several studies have demonstrated that the face that contains a combination of highly feminine and masculine characteristics may obtain a score that recommends average masculinity in the other racial division, but whether this is true for the African population is not yet known. Therefore, the aim o...
Memory impairment is a neurodegenerative condition that is associated with poor cognition. Aluminium chloride (AlCl3) is a neurotoxic agent that disrupts the structure-function of the brain, leading to impaired cognition and memory. Buccholzia coriacea is traditionally reputed to boost memory. This ...