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Haematopathic Assessment of Moringa oleifera Seed Oil in Cadmium and Herbal Alcholic Beverage Induced Blood-Cells Damaged in Wistar Rats

Omotoso OD, Abdullahi AA, Kokori BT, Onoja-Alexander MO, Olorunnado SE

Haematopathic Assessment of Moringa oleifera Seed Oil in Cadmium and Herbal Alcholic Beverage Induced Blood-Cells Damaged in Wistar Rats

This study was targeted at investing the effects of Moringa oleifera seed oil in cadmium and herbal alcoholic beverage induced haematological disorders in Wistar rats. The investigated haematological parameters included haematocrit (HCT), haemoglobin (HGB), lymphocytes (LYM), mean corpuscular haemoglobin concentration (MCHC), red and white blood cells counts (RBC & WBC), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and pack cell volume (PCV). Exposure to both CdSO and herbal alcoholic beverage were 4 significantly (P<0.05) reduced the amounts of WBC and MCHC. MCV values increased at (P<0.05) after the Moringa oleifera seed oil treatment but MCV estimates with Cd exposure showed a decrease as compared with herbal alcoholic beverage with an elevation at (P<0.05) in (MCV). MCH levels increased in both herbal alcoholic beverage and Moringa oleifera seed oil (P<0.05) whereas PCV level increased in Cd and HAB at (P<0.05) as compared with control and treatment groups, while increased in (LYM) counts were observed at significant level (P<0.05) in Cd and HAB as compared with control and treatment groups. The exposed animals showed some haematological disorders in respects to the observed parameters in Cd and HAB, meanwhile, ameliorative properties were examined in line with the above results in the treatment groups with Moringa oleifera.

Key Words: Moringa oleifera, Haematology, Herbal Alcoholic Beverage, Cadmium, Blood Cells

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